A 32 FULL FACTORIAL DESIGN FOR TOPICAL CONTROLLED RELEASETAZAROTENE MICROSPONGE USING HPMC GEL

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formulation of topical bioadhesive gel of aceclofenac using 3-level factorial design

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Formulation of Topical Bioadhesive Gel of Aceclofenac Using 3-Level Factorial Design

The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...

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ژورنال

عنوان ژورنال: International Journal of Applied Pharmaceutics

سال: 2019

ISSN: 0975-7058

DOI: 10.22159/ijap.2019v11i5.34496